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2KTD

Solution structure of mouse lipocalin-type prostaglandin D synthase / substrate analog (U-46619) complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AProstaglandin-H2 D-isomerasepolymer16718585.81UniProt (O09114)
Pfam (PF00061)
In PDB
Mus musculus (mouse)Lipocalin-type prostaglandin-D synthase, Glutathione-independent PGD synthetase, Prostaglandin-D2 synthase, PGD2 synthase, PGDS2, PGDS
2A(5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acidnon-polymer350.51Chemie (PUC)
Sequence modifications
A: 25 - 189 (UniProt: O09114)
PDBExternal DatabaseDetails
Gly 23-expression tag
Ser 24-expression tag
Ala 89Cys 89engineered mutation
Ala 186Cys 186engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight18585.8
Non-Polymers*Number of molecules1
Total formula weight350.5
All*Total formula weight18936.3
*Water molecules are not included.

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PDB entries from 2024-10-02

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