2KOY

Structure of the E1064A mutant of the N-domain of Wilson Disease Associated Protein

Summary for 2KOY

• Entry DOI: 10.2210/pdb2koy/pdb
• Related: 2ARF
• NMR Information: BMRB: 16536
• Descriptor: Copper-transporting ATPase 2 (1 entity in total)
• Functional Keywords: atp7b, wilson disease, atpase, copper transport, atp binding, atp-binding, disease mutation, golgi apparatus, hydrolase, ion transport, magnesium, membrane, metal-binding, mitochondrion, nucleotide-binding, phosphoprotein, transmembrane, transport, metal transport
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 14752.18

Authors

Dmitriev, O.Y. (deposition date: 2009-10-03, release date: 2010-12-15, Last modification date: 2021-10-13)

• Primary citation: Dmitriev, O.Y.,Bhattacharjee, A.,Nokhrin, S.,Uhlemann, E.M.,Lutsenko, S.; Difference in stability of the N-domain underlies distinct intracellular properties of the E1064A and H1069Q mutants of copper-transporting ATPase ATP7B.; J. Biol. Chem., 286:16355-16362, 2011; PubMed: 21398519; DOI: 10.1074/jbc.M110.198101

Experimental method

SOLUTION NMR