2KH6
Solution Structure of cis-5R,6S-thymine glycol opposite complementary adenine in duplex DNA
Summary for 2KH6
Entry DOI | 10.2210/pdb2kh6/pdb |
Related | 2KH5 |
NMR Information | BMRB: 16225 |
Descriptor | 5'-D(*GP*TP*GP*CP*GP*(CTG)P*GP*TP*TP*TP*GP*T)-3', 5'-D(*AP*CP*AP*AP*AP*CP*AP*CP*GP*CP*AP*C)-3' (2 entities in total) |
Functional Keywords | thymine glycol, dna |
Total number of polymer chains | 2 |
Total formula weight | 7358.82 |
Authors | Brown, K.L. (deposition date: 2009-03-24, release date: 2010-03-02, Last modification date: 2024-05-01) |
Primary citation | Brown, K.L.,Roginskaya, M.,Zou, Y.,Altamirano, A.,Basu, A.K.,Stone, M.P. Binding of the human nucleotide excision repair proteins XPA and XPC/HR23B to the 5R-thymine glycol lesion and structure of the cis-(5R,6S) thymine glycol epimer in the 5'-GTgG-3' sequence: destabilization of two base pairs at the lesion site Nucleic Acids Res., 38:428-440, 2010 Cited by PubMed: 19892827DOI: 10.1093/nar/gkp844 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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