2KDH
The Solution Structure of Human Cardiac Troponin C in complex with the Green Tea Polyphenol; (-)-epigallocatechin-3-gallate
Summary for 2KDH
| Entry DOI | 10.2210/pdb2kdh/pdb |
| NMR Information | BMRB: 17243 |
| Descriptor | Troponin C, slow skeletal and cardiac muscles, CALCIUM ION, (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate (3 entities in total) |
| Functional Keywords | ca2+ binding protein, ca2+ sensitizer, troponin c, egcg, acetylation, calcium, cardiomyopathy, disease mutation, muscle protein, polymorphism, structural protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 8907.73 |
| Authors | Robertson, I.M.,Li, M.X.,Sykes, B.D. (deposition date: 2009-01-09, release date: 2009-06-16, Last modification date: 2022-03-16) |
| Primary citation | Robertson, I.M.,Li, M.X.,Sykes, B.D. Solution structure of human cardiac troponin C in complex with the green tea polyphenol, (-)-epigallocatechin 3-gallate J.Biol.Chem., 284:23012-23023, 2009 Cited by PubMed: 19542563DOI: 10.1074/jbc.M109.021352 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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