2KDH

The Solution Structure of Human Cardiac Troponin C in complex with the Green Tea Polyphenol; (-)-epigallocatechin-3-gallate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 2

Chain	Residue
A	MET137
A	ASP141
A	LYS142
A	ASN143
A	ASP145

---

site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE KDH A 1

Chain	Residue
A	ILE112

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site_id	AC3
Number of Residues	11
Details

Chain	Residue
A	LEU121
A	THR124
A	GLU135
A	LEU136
A	PHE156
A	MET157
A	VAL160
A	GLU161
A	MET90
A	PHE104
A	MET120

---

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DKNADGYIDldEL

Chain	Residue	Details
A	ASP105-LEU117
A	ASP141-PHE153

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	35
Details	Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	33
Details	Domain: {"description":"EF-hand 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P19123","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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