2K9Y
EphA2 dimeric structure in the lipidic bicelle at pH 5.0
Summary for 2K9Y
Entry DOI | 10.2210/pdb2k9y/pdb |
Related | 2k1k 2k1l |
NMR Information | BMRB: 16005 |
Descriptor | Ephrin type-A receptor 2 (2 entities in total) |
Functional Keywords | receptor tyrosine kinase, membrane protein, dimeric transmembrane domain, ephrin receptor, atp-binding, glycoprotein, kinase, membrane, nucleotide-binding, phosphoprotein, polymorphism, receptor, transferase, transmembrane, tyrosine-protein kinase |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Single-pass type I membrane protein: P29317 |
Total number of polymer chains | 2 |
Total formula weight | 8566.10 |
Authors | Mayzel, M.L.,Bocharov, E.V.,Volynsky, P.E.,Arseniev, A.S. (deposition date: 2008-10-27, release date: 2009-08-11, Last modification date: 2024-05-15) |
Primary citation | Bocharov, E.V.,Mayzel, M.L.,Volynsky, P.E.,Mineev, K.S.,Tkach, E.N.,Ermolyuk, Y.S.,Schulga, A.A.,Efremov, R.G.,Arseniev, A.S. Left-Handed Dimer of EphA2 Transmembrane Domain: Helix Packing Diversity among Receptor Tyrosine Kinases Biophys.J., 98:881-889, 2010 Cited by PubMed: 20197042DOI: 10.1016/j.bpj.2009.11.008 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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