2K3W
NMR structure of VPS4A-MIT-CHMP6
Summary for 2K3W
Entry DOI | 10.2210/pdb2k3w/pdb |
Descriptor | Vacuolar protein sorting-associating protein 4A, Charged multivesicular body protein 6 (2 entities in total) |
Functional Keywords | esrct-iii, chmp6, mit, atp-binding, membrane, nucleotide-binding, protein transport, transport, coiled coil, endosome, lipoprotein, myristate |
Biological source | Homo sapiens (human) More |
Cellular location | Prevacuolar compartment membrane; Peripheral membrane protein: Q9UN37 Endomembrane system: Q96FZ7 |
Total number of polymer chains | 2 |
Total formula weight | 11700.34 |
Authors | Kieffer, C.,Skalicky, J.J.,Morita, E.,De Domini, I.,Ward, D.M.,Kaplan, J.,Sundquist, W.I. (deposition date: 2008-05-19, release date: 2008-10-28, Last modification date: 2024-05-29) |
Primary citation | Kieffer, C.,Skalicky, J.J.,Morita, E.,De Domenico, I.,Ward, D.M.,Kaplan, J.,Sundquist, W.I. Two distinct modes of ESCRT-III recognition are required for VPS4 functions in lysosomal protein targeting and HIV-1 budding Dev.Cell, 15:62-73, 2008 Cited by PubMed: 18606141DOI: 10.1016/j.devcel.2008.05.014 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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