2K2J
NMR solution structure of the split PH domain from Phospholipase C gamma 2
Summary for 2K2J
| Entry DOI | 10.2210/pdb2k2j/pdb |
| NMR Information | BMRB: 15707 |
| Descriptor | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 (1 entity in total) |
| Functional Keywords | two sheeted beta barrel, c-terminal helix, calcium, hydrolase, lipid degradation, phosphoprotein, polymorphism, sh2 domain, sh3 domain, transducer, signaling protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 14246.83 |
| Authors | Harris, R.,Bunney, T.D.,Katan, M.,Driscoll, P.C. (deposition date: 2008-04-02, release date: 2008-09-09, Last modification date: 2020-02-19) |
| Primary citation | Walliser, C.,Retlich, M.,Harris, R.,Everett, K.L.,Josephs, M.B.,Vatter, P.,Esposito, D.,Driscoll, P.C.,Katan, M.,Gierschik, P.,Bunney, T.D. Rac Regulates Its Effector Phospholipase C{gamma}2 through Interaction with a Split Pleckstrin Homology Domain. J.Biol.Chem., 283:30351-30362, 2008 Cited by PubMed: 18728011DOI: 10.1074/jbc.M803316200 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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