2K2J

NMR solution structure of the split PH domain from Phospholipase C gamma 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2	polymer	124	14246.8	1	UniProt (P16885)	Homo sapiens (human)	Phosphoinositide phospholipase C, PLC-gamma-2, Phospholipase C-gamma-2, PLC-IV

Sequence modifications

A: 8 - 51 (UniProt: P16885)

PDB	External Database	Details
Gly 1	-	expression tag
Gly 2	-	expression tag
Gly 3	-	expression tag
Ser 4	-	expression tag
Gly 5	-	expression tag
Gly 6	-	expression tag
Ser 7	-	expression tag

A: 52 - 124 (UniProt: P16885)

PDB	External Database	Details
Asp 94	Tyr 883	variant

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	14246.8
All*	Total formula weight	14246.8

*Water molecules are not included.