2JXY
Solution structure of the hemopexin-like domain of MMP12
Summary for 2JXY
Entry DOI | 10.2210/pdb2jxy/pdb |
NMR Information | BMRB: 7414,7415,15578 |
Descriptor | Macrophage metalloelastase, CALCIUM ION (2 entities in total) |
Functional Keywords | b-sheet hydrophobic core, calcium, extracellular matrix, glycoprotein, hydrolase, metal-binding, metalloprotease, polymorphism, protease, secreted, zinc, zymogen |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted, extracellular space, extracellular matrix (Probable): P39900 |
Total number of polymer chains | 1 |
Total formula weight | 23240.53 |
Authors | Bertini, I.,Calderone, V.,Fragai, M.,Jaiswal, R.,Luchinat, C.,Melikian, M. (deposition date: 2007-12-01, release date: 2008-05-27, Last modification date: 2022-03-16) |
Primary citation | Bertini, I.,Calderone, V.,Fragai, M.,Jaiswal, R.,Luchinat, C.,Melikian, M.,Mylonas, E.,Svergun, D.I. Evidence of reciprocal reorientation of the catalytic and hemopexin-like domains of full-length MMP-12 J.Am.Chem.Soc., 130:7011-7021, 2008 Cited by PubMed: 18465858DOI: 10.1021/ja710491y PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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