2JPA

Structure of the Wilms Tumor Suppressor Protein Zinc Finger Domain Bound to DNA

Summary for 2JPA

• Entry DOI: 10.2210/pdb2jpa/pdb
• Related: 2JP9 2PRT
• NMR Information: BMRB: 15533
• Descriptor: DNA (5'-D(P*DCP*DGP*DCP*DGP*DGP*DGP*DGP*DGP*DCP*DGP*DTP*DCP*DTP*DG)-3'), DNA (5'-D(P*DCP*DAP*DGP*DAP*DCP*DGP*DCP*DCP*DCP*DCP*DCP*DGP*DCP*DG)-3'), Wilms tumor 1, ... (4 entities in total)
• Functional Keywords: dna binding, nucleic acid recognition, residual dipolar coupling, zinc finger, metal-binding, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 23315.88

Authors

Stoll, R.,Lee, B.M.,Debler, E.W.,Laity, J.H.,Wilson, I.A.,Dyson, H.J.,Wright, P.E. (deposition date: 2007-05-01, release date: 2007-10-30, Last modification date: 2020-02-05)

• Primary citation: Stoll, R.,Lee, B.M.,Debler, E.W.,Laity, J.H.,Wilson, I.A.,Dyson, H.J.,Wright, P.E.; Structure of the wilms tumor suppressor protein zinc finger domain bound to DNA; J.Mol.Biol., 372:1227-1245, 2007; PubMed: 17716689; DOI: 10.1016/j.jmb.2007.07.017

Experimental method

SOLUTION NMR