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2JHH

Structure of globular heads of M-ficolin at acidic pH

Summary for 2JHH
Entry DOI10.2210/pdb2jhh/pdb
Related2JHI 2JHK 2JHL 2JHM
DescriptorFICOLIN-1, CALCIUM ION (3 entities in total)
Functional Keywordslectin, collagen, acidic ph, complement, sugar-binding protein, glycoprotein, polymorphism, innate immunity, sugar binding protein
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains2
Total formula weight48832.00
Authors
Garlatti, V.,Martin, L.,Gout, E.,Reiser, J.B.,Arlaud, G.J.,Thielens, N.M.,Gaboriaud, C. (deposition date: 2007-02-22, release date: 2007-10-09, Last modification date: 2019-04-03)
Primary citationGarlatti, V.,Martin, L.,Gout, E.,Reiser, J.B.,Fujita, T.,Arlaud, G.J.,Thielens, N.M.,Gaboriaud, C.
Structural basis for innate immune sensing by M-ficolin and its control by a pH-dependent conformational switch.
J. Biol. Chem., 282:35814-35820, 2007
Cited by
PubMed: 17897951
DOI: 10.1074/jbc.M705741200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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