2J6L

Structure of aminoadipate-semialdehyde dehydrogenase

Summary for 2J6L

Entry DOI	10.2210/pdb2j6l/pdb
Descriptor	ALDEHYDE DEHYDROGENASE FAMILY 7 MEMBER A1, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, BROMIDE ION, ... (5 entities in total)
Functional Keywords	aldehyde dehydrogenase, nad, reductase, oxidoreductase, lysine catabolism
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Mitochondrion . Isoform 2: Cytoplasm, cytosol: P49419
Total number of polymer chains	8
Total formula weight	440062.82
Authors	Bunkoczi, G.,Guo, K.,Debreczeni, J.E.,Smee, C.,Arrowsmith, C.,Edwards, A.,Sundstrom, M.,Weigelt, J.,von Delft, F.,Oppermann, U. (deposition date: 2006-09-29, release date: 2006-10-12, Last modification date: 2023-12-13)
Primary citation	Brocker, C.,Lassen, N.,Estey, T.,Pappa, A.,Cantore, M.,Orlova, V.V.,Chavakis, T.,Kavanagh, K.L.,Oppermann, U.,Vasiliou, V. Aldehyde Dehydrogenase 7A1 (Aldh7A1) is a Novel Enzyme Involved in Cellular Defense Against Hyperosmotic Stress. J.Biol.Chem., 285:18452-, 2010 Cited by PubMed: 20207735 DOI: 10.1074/JBC.M109.077925 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation