2J06

Crystal structure of the RasGAP SH3 domain at 1.8 Angstrom resolution

Summary for 2J06

Entry DOI	10.2210/pdb2j06/pdb
Related	1WER 1WQ1 2J05
Descriptor	RAS GTPASE-ACTIVATING PROTEIN 1 (2 entities in total)
Functional Keywords	gtpase activation, sh3 domain, sh2 domain, src homology 3, ras signaling pathway, gtpase activating protein, proto-oncogene, phosphorylation, disease mutation, signal transduction
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm: P20936
Total number of polymer chains	2
Total formula weight	15530.67
Authors	Ross, B.,Gajhede, M.,Kristensen, O. (deposition date: 2006-08-01, release date: 2007-01-02, Last modification date: 2011-07-13)
Primary citation	Ross, B.,Kristensen, O.,Favre, D.,Walicki, J.,Kastrup, J.S.,Widmann, C.,Gajhede, M. High Resolution Crystal Structures of the P120 Rasgap SH3 Domain. Biochem.Biophys.Res.Commun., 353:463-, 2007 Cited by PubMed: 17188236 DOI: 10.1016/J.BBRC.2006.12.044 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation