2I32

Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly

Summary for 2I32

Entry DOI	10.2210/pdb2i32/pdb
Descriptor	Anti-Silencing Factor 1 paralog a, Histone Regulatory homolog A (3 entities in total)
Functional Keywords	histone deposition, chromatin regulation, histone chaperones, asf1, hira, caf-1, replication chaperone
Biological source	Homo sapiens (human) More
Cellular location	Nucleus : Q9Y294 P54198
Total number of polymer chains	4
Total formula weight	54106.06
Authors	Marmorstein, R.,Tang, Y. (deposition date: 2006-08-17, release date: 2006-09-19, Last modification date: 2023-08-30)
Primary citation	Tang, Y.,Poustovoitov, M.V.,Zhao, K.,Garfinkel, M.,Canutescu, A.,Dunbrack, R.,Adams, P.D.,Marmorstein, R. Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly. Nat.Struct.Mol.Biol., 13:921-929, 2006 Cited by PubMed: 16980972 DOI: 10.1038/nsmb1147 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation