2I32
Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Anti-Silencing Factor 1 paralog a | polymer | 182 | 20837.1 | 2 | UniProt (Q9Y294) Pfam (PF04729) In PDB | Homo sapiens (human) | ASF1a protein, ASF1 anti-silencing function 1 homolog A, Hypothetical protein FLJ22085, Anti-silencing function 1A, CGI-98 protein, CIA |
2 | E, F | Histone Regulatory homolog A | polymer | 57 | 6216.0 | 2 | UniProt (P54198) In PDB | Homo sapiens (human) | HIRA protein, TUP1-like enhancer of split protein 1 |
3 | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 157 (UniProt: Q9Y294)
E, F: 425 - 472 (UniProt: P54198)
PDB | External Database | Details |
---|---|---|
Met -24 | - | cloning artifact |
Gly -23 | - | cloning artifact |
Ser -22 | - | cloning artifact |
Ser -21 | - | cloning artifact |
His -20 | - | expression tag |
His -19 | - | expression tag |
His -18 | - | expression tag |
His -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
Asp -14 | - | cloning artifact |
Tyr -13 | - | cloning artifact |
Asp -12 | - | cloning artifact |
Ile -11 | - | cloning artifact |
Pro -10 | - | cloning artifact |
Thr -9 | - | cloning artifact |
Thr -8 | - | cloning artifact |
Glu -7 | - | cloning artifact |
Asn -6 | - | cloning artifact |
Leu -5 | - | cloning artifact |
Tyr -4 | - | cloning artifact |
Phe -3 | - | cloning artifact |
Gln -2 | - | cloning artifact |
Gly -1 | - | cloning artifact |
Ser 0 | - | cloning artifact |
PDB | External Database | Details |
---|---|---|
Ser 416 | - | cloning artifact |
Glu 417 | - | cloning artifact |
Asn 418 | - | cloning artifact |
Leu 419 | - | cloning artifact |
Tyr 420 | - | cloning artifact |
Phe 421 | - | cloning artifact |
Gln 422 | - | cloning artifact |
Gly 423 | - | cloning artifact |
Ser 424 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 54106.1 | |
All* | Total formula weight | 54106.1 |