2I19
T. Brucei farnesyl diphosphate synthase complexed with bisphosphonate
Summary for 2I19
Entry DOI | 10.2210/pdb2i19/pdb |
Descriptor | Farnesyl pyrophosphate synthase, MAGNESIUM ION, [2-(PYRIDIN-2-YLAMINO)ETHANE-1,1-DIYL]BIS(PHOSPHONIC ACID), ... (4 entities in total) |
Functional Keywords | protein-bisphosphonate complex, transferase |
Biological source | Trypanosoma brucei |
Total number of polymer chains | 2 |
Total formula weight | 89661.56 |
Authors | Cao, R.,Mao, J.,Gao, Y.,Robinson, H.,Odeh, S.,Goddard, A.,Oldfield, E. (deposition date: 2006-08-13, release date: 2006-10-17, Last modification date: 2023-08-30) |
Primary citation | Mao, J.,Mukherjee, S.,Zhang, Y.,Cao, R.,Sanders, J.M.,Song, Y.,Zhang, Y.,Meints, G.A.,Gao, Y.G.,Mukkamala, D.,Hudock, M.P.,Oldfield, E. Solid-state NMR, crystallographic, and computational investigation of bisphosphonates and farnesyl diphosphate synthase-bisphosphonate complexes. J.Am.Chem.Soc., 128:14485-14497, 2006 Cited by PubMed: 17090032DOI: 10.1021/ja061737c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.28 Å) |
Structure validation
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