2I19
T. Brucei farnesyl diphosphate synthase complexed with bisphosphonate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Farnesyl pyrophosphate synthase | polymer | 390 | 44475.7 | 2 | UniProt (Q86C09) Pfam (PF00348) | Trypanosoma brucei | |
| 2 | C, D, E, G, H... (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 3 | F, J (A, B) | [2-(PYRIDIN-2-YLAMINO)ETHANE-1,1-DIYL]BIS(PHOSPHONIC ACID) | non-polymer | 282.1 | 2 | Chemie (1BY) | [2-(2-pyridinylamino)ethylidene]-1,1-bisphosphonate | ||
| 4 | K, L (A, B) | water | water | 18.0 | 358 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 367 (UniProt: Q86C09)
| PDB | External Database | Details |
|---|---|---|
| Met -22 | - | cloning artifact |
| Gly -21 | - | cloning artifact |
| Ser -20 | - | cloning artifact |
| Ser -19 | - | cloning artifact |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| Ser -12 | - | cloning artifact |
| Ser -11 | - | cloning artifact |
| Gly -10 | - | cloning artifact |
| Leu -9 | - | cloning artifact |
| Val -8 | - | cloning artifact |
| Pro -7 | - | cloning artifact |
| Arg -6 | - | cloning artifact |
| Gly -5 | - | cloning artifact |
| Ser -4 | - | cloning artifact |
| His -3 | - | cloning artifact |
| Met -2 | - | cloning artifact |
| Ala -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 88951.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 710.1 | |
| All* | Total formula weight | 89661.6 |
