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2HZ9

Crystal structure of Lys12Val/Asn95Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.70 angstrom resolution.

Summary for 2HZ9
Entry DOI10.2210/pdb2hz9/pdb
Related1JQZ
DescriptorHeparin-binding growth factor 1, SULFATE ION, FORMIC ACID, ... (4 entities in total)
Functional Keywordsbeta-trefoil, hormone-growth factor complex, hormone/growth factor
Biological sourceHomo sapiens (human)
Cellular locationSecreted: P05230
Total number of polymer chains2
Total formula weight33555.59
Authors
Dubey, V.K.,Lee, J.,Somasundaram, T.,Blaber, M. (deposition date: 2006-08-08, release date: 2007-06-19, Last modification date: 2023-08-30)
Primary citationDubey, V.K.,Lee, J.,Somasundaram, T.,Blaber, S.,Blaber, M.
Spackling the Crack: Stabilizing Human Fibroblast Growth Factor-1 by Targeting the N and C terminus beta-Strand Interactions
J.Mol.Biol., 371:256-268, 2007
Cited by
PubMed: 17570396
DOI: 10.1016/j.jmb.2007.05.065
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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