2HPP

Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human ppack-thrombin

Summary for 2HPP

• Entry DOI: 10.2210/pdb2hpp/pdb
• Related: 2HPQ
• Related PRD ID: PRD_000021
• Descriptor: ALPHA-THROMBIN LIGHT CHAIN, ALPHA-THROMBIN HEAVY CHAIN, Prothrombin, ... (5 entities in total)
• Functional Keywords: hydrolase-hydrolase inhibitor complex, serine proteinase, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted, extracellular space: P00734 P00734 P00735
• Total number of polymer chains: 3
• Total formula weight: 43164.36

Authors

Tulinsky, A.,Padmanabhan, K. (deposition date: 1993-04-28, release date: 1994-01-31, Last modification date: 2013-02-27)

• Primary citation: Arni, R.K.,Padmanabhan, K.,Padmanabhan, K.P.,Wu, T.P.,Tulinsky, A.; Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human PPACK-thrombin.; Biochemistry, 32:4727-4737, 1993; PubMed: 8387813; DOI: 10.1021/bi00069a006

Experimental method

X-RAY DIFFRACTION (3.3 Å)