2HPP
Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human ppack-thrombin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | ALPHA-THROMBIN LIGHT CHAIN | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | |
| 2 | B (H) | ALPHA-THROMBIN HEAVY CHAIN | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | |
| 3 | C (P) | Prothrombin | polymer | 79 | 8836.6 | 1 | UniProt (P00735) Pfam (PF00051) | Bos Taurus (Bovine) | Coagulation factor II |
| 4 | D (H) | D-phenylalanyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]-L-prolinamide | non-polymer | 451.0 | 1 | BIRD (PRD_000021) Chemie (0G7) | |||
| 5 | E, F, G (L, H, P) | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence modifications
P: 301 - 379 (UniProt: P00735)
| PDB | External Database | Details |
|---|---|---|
| Asn 375 | Asp 288 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 42713.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 451.0 | |
| All* | Total formula weight | 43164.4 |
