2HHX
O6-methyl-guanine in the polymerase template preinsertion site
Summary for 2HHX
Entry DOI | 10.2210/pdb2hhx/pdb |
Related | 2HHQ 2HHS 2HHT 2HHU 2HHV 2HHW 2HHY |
Related PRD ID | PRD_900003 |
Descriptor | 5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*G)-3', 5'-D(*CP*AP*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', DNA Polymerase I, ... (6 entities in total) |
Functional Keywords | dna polymerase i, dna replication, klenow fragment, protein-dna complex, o6-methyl-guanine, transferase-dna complex, transferase/dna |
Biological source | Geobacillus stearothermophilus More |
Total number of polymer chains | 3 |
Total formula weight | 74022.22 |
Authors | Warren, J.J.,Forsberg, L.J.,Beese, L.S. (deposition date: 2006-06-28, release date: 2006-12-12, Last modification date: 2024-02-14) |
Primary citation | Warren, J.J.,Forsberg, L.J.,Beese, L.S. The structural basis for the mutagenicity of O6-methyl-guanine lesions. Proc.Natl.Acad.Sci.Usa, 103:19701-19706, 2006 Cited by PubMed: 17179038DOI: 10.1073/pnas.0609580103 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.26 Å) |
Structure validation
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