2HFG

Crystal structure of hBR3 bound to CB3s-Fab

Summary for 2HFG

• Entry DOI: 10.2210/pdb2hfg/pdb
• Related: 2hff
• Descriptor: CB3s Fab light chain (kappa), CB3s Fab heavy chain, Tumor necrosis factor receptor superfamily member 13C, ... (4 entities in total)
• Functional Keywords: fab fragment, tnfrsf, antibody-receptor complex, crd, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type III membrane protein (Probable): Q96RJ3
• Total number of polymer chains: 3
• Total formula weight: 52988.36

Authors

Hymowitz, S.G. (deposition date: 2006-06-23, release date: 2006-11-07, Last modification date: 2024-04-03)

• Primary citation: Lee, C.V.,Hymowitz, S.G.,Wallweber, H.J.,Gordon, N.C.,Billeci, K.L.,Tsai, S.P.,Compaan, D.M.,Yin, J.,Gong, Q.,Kelley, R.F.,Deforge, L.E.,Martin, F.,Starovasnik, M.A.,Fuh, G.; Synthetic anti-BR3 antibodies that mimic BAFF binding and target both human and murine B cells.; Blood, 108:3103-3111, 2006; PubMed: 16840730; DOI: 10.1182/blood-2006-03-011031

Experimental method

X-RAY DIFFRACTION (2.61 Å)