2HFG
Crystal structure of hBR3 bound to CB3s-Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | CB3s Fab light chain (kappa) | polymer | 214 | 23250.8 | 1 | UniProt (Q6PIH7) | Homo sapiens (human) | |
| 2 | B (H) | CB3s Fab heavy chain | polymer | 232 | 24414.5 | 1 | UniProt (Q6N093) Pfam (PF07686) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C (R) | Tumor necrosis factor receptor superfamily member 13C | polymer | 51 | 5323.1 | 1 | UniProt (Q96RJ3) Pfam (PF09256) | Homo sapiens (human) | B cell-activating factor receptor, BAFF receptor, BAFF-R, BLyS receptor 3, CD268 antigen |
| 4 | D, E, F (L, H, R) | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
R: 7 - 54 (UniProt: Q96RJ3)
| PDB | External Database | Details |
|---|---|---|
| Gly 4 | - | cloning artifact |
| Ser 5 | - | cloning artifact |
| Tyr 6 | - | cloning artifact |
| Asn 20 | Val 20 | engineered mutation |
| Pro 27 | Leu 27 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 52988.4 | |
| All* | Total formula weight | 52988.4 |
