2H7B
Solution structure of the eTAFH domain from the human leukemia-associated fusion protein AML1-ETO
Summary for 2H7B
Entry DOI | 10.2210/pdb2h7b/pdb |
NMR Information | BMRB: 7147 |
Descriptor | Core-binding factor, ML1-ETO (1 entity in total) |
Functional Keywords | 4 helix bundle, transcription |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 11887.72 |
Authors | Plevin, M.J.,Zhang, J.,Guo, C.,Roeder, R.G.,Ikura, M. (deposition date: 2006-06-01, release date: 2006-07-11, Last modification date: 2024-05-29) |
Primary citation | Plevin, M.J.,Zhang, J.,Guo, C.,Roeder, R.G.,Ikura, M. The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domain Proc.Natl.Acad.Sci.USA, 103:10242-10247, 2006 Cited by PubMed: 16803958DOI: 10.1073/pnas.0603463103 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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