2H7B
Solution structure of the eTAFH domain from the human leukemia-associated fusion protein AML1-ETO
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Core-binding factor, ML1-ETO | polymer | 105 | 11887.7 | 1 | UniProt (Q7Z4J5) Pfam (PF07531) UniProt (by SIFTS) (Q06455) In PDB | Homo sapiens (human) | runt domain, alpha subunit 2, translocated to 1, cyclin D-related |
Sequence modifications
A: 1 - 103 (UniProt: Q7Z4J5)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
| Ala 80 | Cys 162 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 11887.7 | |
| All* | Total formula weight | 11887.7 |
