2H5K

Crystal Structure of Complex Between the Domain-Swapped Dimeric Grb2 SH2 Domain and Shc-Derived Ligand, Ac-NH-pTyr-Val-Asn-NH2

Summary for 2H5K

• Entry DOI: 10.2210/pdb2h5k/pdb
• Related: 2H46
• Descriptor: Growth factor receptor-bound protein 2, Shc-Derived Ligand, CACODYLATE ION, ... (4 entities in total)
• Functional Keywords: domain-swapping, protein-phosphopeptide complex, hormone-growth factor complex, hormone/growth factor
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus : P62993
• Total number of polymer chains: 3
• Total formula weight: 28010.37

Authors

Benfield, A.P.,Whiddon, B.B.,Martin, S.F. (deposition date: 2006-05-26, release date: 2006-08-15, Last modification date: 2017-10-18)

• Primary citation: Benfield, A.P.,Whiddon, B.B.,Clements, J.H.,Martin, S.F.; Structural and energetic aspects of Grb2-SH2 domain-swapping.; Arch.Biochem.Biophys., 462:47-53, 2007; PubMed: 17466257; DOI: 10.1016/j.abb.2007.03.010

Experimental method

X-RAY DIFFRACTION (3.25 Å)