2H11

Amino-terminal Truncated Thiopurine S-Methyltransferase Complexed with S-Adenosyl-L-Homocysteine

Summary for 2H11

• Entry DOI: 10.2210/pdb2h11/pdb
• Descriptor: Thiopurine S-methyltransferase, THIOCYANATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ... (5 entities in total)
• Functional Keywords: binary protein-cofactor complex, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 55141.47

Authors

Horton, J.R.,Cheng, X. (deposition date: 2006-05-15, release date: 2006-11-21, Last modification date: 2023-08-30)

• Primary citation: Wu, H.,Horton, J.R.,Battaile, K.,Allali-Hassani, A.,Martin, F.,Zeng, H.,Loppnau, P.,Vedadi, M.,Bochkarev, A.,Plotnikov, A.N.,Cheng, X.; Structural basis of allele variation of human thiopurine-S-methyltransferase.; Proteins, 67:198-208, 2007; PubMed: 17243178; DOI: 10.1002/prot.21272

Experimental method

X-RAY DIFFRACTION (1.89 Å)