2H11
Amino-terminal Truncated Thiopurine S-Methyltransferase Complexed with S-Adenosyl-L-Homocysteine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Thiopurine S-methyltransferase | polymer | 232 | 26646.7 | 2 | UniProt (O43213) Pfam (PF05724) UniProt (by SIFTS) (P51580) In PDB | Homo sapiens (human) | Thiopurine methyltransferase |
| 2 | A, B | THIOCYANATE ION | non-polymer | 58.1 | 4 | Chemie (SCN) | |||
| 3 | A, B | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 4 | A, B | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 282.3 | 3 | Chemie (B3P) | |||
| 5 | water | water | 18.0 | 322 | Chemie (HOH) |
Sequence modifications
A, B: 17 - 245 (UniProt: O43213)
| PDB | External Database | Details |
|---|---|---|
| Gly 14 | - | cloning artifact |
| Ser 15 | - | cloning artifact |
| Thr 16 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53293.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1848.2 | |
| All* | Total formula weight | 55141.5 |
