2GV2
MDM2 in complex with an 8-mer p53 peptide analogue
Summary for 2GV2
Entry DOI | 10.2210/pdb2gv2/pdb |
Related | 1RV1 1T4E 1T4F 1YCR |
Descriptor | E3 ubiquitin-protein ligase Mdm2, 8-MER P53 PEPTIDE ANALOGUE (3 entities in total) |
Functional Keywords | optimized protein-protein interaction. synthetic peptide. alpha helix binding protein, ligase |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus, nucleoplasm: Q00987 |
Total number of polymer chains | 2 |
Total formula weight | 13787.12 |
Authors | Schubert, C.,Sakurai, K. (deposition date: 2006-05-02, release date: 2006-09-05, Last modification date: 2023-11-15) |
Primary citation | Sakurai, K.,Schubert, C.,Kahne, D. Crystallographic Analysis of an 8-mer p53 Peptide Analogue Complexed with MDM2. J.Am.Chem.Soc., 128:11000-11001, 2006 Cited by PubMed: 16925398DOI: 10.1021/ja063102j PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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