2GS0
NMR structure of the complex between the PH domain of the Tfb1 subunit from TFIIH and the activation domain of p53
Summary for 2GS0
| Entry DOI | 10.2210/pdb2gs0/pdb |
| NMR Information | BMRB: 6225 |
| Descriptor | RNA polymerase II transcription factor B subunit 1, Cellular tumor antigen p53 (2 entities in total) |
| Functional Keywords | p53, tfiih, tfb1, activation, transcription, ph domain |
| Biological source | Saccharomyces cerevisiae (baker's yeast) More |
| Cellular location | Nucleus: P32776 Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637 |
| Total number of polymer chains | 2 |
| Total formula weight | 18922.37 |
| Authors | Di Lello, P.,Jones, T.N.,Nguyen, B.D.,Legault, P.,Omichinski, J.G. (deposition date: 2006-04-25, release date: 2006-10-31, Last modification date: 2021-10-20) |
| Primary citation | Di Lello, P.,Jenkins, L.M.,Jones, T.N.,Nguyen, B.D.,Hara, T.,Yamaguchi, H.,Dikeakos, J.D.,Appella, E.,Legault, P.,Omichinski, J.G. Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53. Mol.Cell, 22:731-740, 2006 Cited by PubMed: 16793543DOI: 10.1016/j.molcel.2006.05.007 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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