2GS0
NMR structure of the complex between the PH domain of the Tfb1 subunit from TFIIH and the activation domain of p53
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RNA polymerase II transcription factor B subunit 1 | polymer | 115 | 12903.7 | 1 | UniProt (P32776) Pfam (PF08567) | Saccharomyces cerevisiae (baker's yeast) | RNA polymerase II transcription factor B p73 subunit, RNA polymerase II transcription factor B 73 kDa subunit |
| 2 | B (B) | Cellular tumor antigen p53 | polymer | 54 | 6018.7 | 1 | UniProt (P04637) Pfam (PF08563) Pfam (PF18521) | Homo sapiens (human) | Tumor suppressor p53 |
Sequence modifications
A: 1 - 115 (UniProt: P32776)
| PDB | External Database | Details |
|---|---|---|
| Pro 1 | Met 1 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 18922.4 | |
| All* | Total formula weight | 18922.4 |
