2GMU

Crystal structure of E coli GDP-4-keto-6-deoxy-D-mannose-3-dehydratase complexed with PLP-glutamate ketimine intermediate

Summary for 2GMU

• Entry DOI: 10.2210/pdb2gmu/pdb
• Related: 2GMS
• Descriptor: Putative pyridoxamine 5-phosphate-dependent dehydrase, WbdK, MAGNESIUM ION, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-D-GLUTAMIC ACID, ... (4 entities in total)
• Functional Keywords: colitose, deoxysugar, aspartate aminotransferase, plp, o-antigen, transferase
• Biological source: Escherichia coli O55:H7
• Total number of polymer chains: 2
• Total formula weight: 89485.69

Authors

Cook, P.D.,Thoden, J.B.,Holden, H.M. (deposition date: 2006-04-07, release date: 2006-09-05, Last modification date: 2023-08-30)

• Primary citation: Cook, P.D.,Thoden, J.B.,Holden, H.M.; The structure of GDP-4-keto-6-deoxy-D-mannose-3-dehydratase: a unique coenzyme B6-dependent enzyme.; Protein Sci., 15:2093-2106, 2006; PubMed: 16943443; DOI: 10.1110/ps.062328306

Experimental method

X-RAY DIFFRACTION (1.9 Å)