2GEH
N-Hydroxyurea, a versatile zinc binding function in the design of metalloenzyme inhibitors
Summary for 2GEH
Entry DOI | 10.2210/pdb2geh/pdb |
Descriptor | Carbonic anhydrase 2, ZINC ION, MERCURY (II) ION, ... (5 entities in total) |
Functional Keywords | carbonic anhydrase, inhibitors, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29831.71 |
Authors | Temperini, C.,Innocenti, A.,Scozzafava, A.,Supuran, C.T. (deposition date: 2006-03-20, release date: 2006-06-20, Last modification date: 2024-02-14) |
Primary citation | Temperini, C.,Innocenti, A.,Scozzafava, A.,Supuran, C.T. N-Hydroxyurea-A versatile zinc binding function in the design of metalloenzyme inhibitors. Bioorg.Med.Chem.Lett., 16:4316-4320, 2006 Cited by PubMed: 16759856DOI: 10.1016/j.bmcl.2006.05.068 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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