2GEH
N-Hydroxyurea, a versatile zinc binding function in the design of metalloenzyme inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Carbonic anhydrase 2 | polymer | 260 | 29289.1 | 1 | UniProt (P00918) Pfam (PF00194) | Homo sapiens (human) | Carbonic anhydrase II, Carbonate dehydratase II, CA-II, Carbonic anhydrase C |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C, D (A) | MERCURY (II) ION | non-polymer | 200.6 | 2 | Chemie (HG) | |||
| 4 | E (A) | N-HYDROXYUREA | non-polymer | 76.1 | 1 | Chemie (NHY) | |||
| 5 | F (A) | water | water | 18.0 | 176 | Chemie (HOH) |
Sequence modifications
A: 2 - 260 (UniProt: P00918)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29289.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 542.6 | |
| All* | Total formula weight | 29831.7 |
