2GD7
The Structure of the Cyclin T-binding domain of Hexim1 reveals the molecular basis for regulation of transcription elongation
Summary for 2GD7
| Entry DOI | 10.2210/pdb2gd7/pdb |
| Descriptor | HEXIM1 protein (1 entity in total) |
| Functional Keywords | hexim1, transcription regulation, transcription elongation, positive transcription elongation factor-b, p-tefb nmr, structure determination, symmetric dimer, coiled coil, maq1, clp-1, edg1, transcription |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 25360.10 |
| Authors | Dames, S.A. (deposition date: 2006-03-15, release date: 2007-06-12, Last modification date: 2021-10-20) |
| Primary citation | Dames, S.A.,Schonichen, A.,Schulte, A.,Barboric, M.,Peterlin, B.M.,Grzesiek, S.,Geyer, M. Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb. Proc.Natl.Acad.Sci.Usa, 104:14312-14317, 2007 Cited by PubMed: 17724342DOI: 10.1073/pnas.0701848104 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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