2GD4

Crystal Structure of the Antithrombin-S195A Factor Xa-Pentasaccharide Complex

Summary for 2GD4

Entry DOI	10.2210/pdb2gd4/pdb
Related PRD ID	PRD_900028
Descriptor	Coagulation factor X, Stuart factor, Stuart-Prower factor, Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain, Coagulation factor, Stuart factor, Stuart-Prower factor, Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain, Antithrombin-III, ... (9 entities in total)
Functional Keywords	serpin, michaelis complex, hydrolase
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	173130.35
Authors	Johnson, D.J.,Li, W.,Adams, T.E.,Huntington, J.A. (deposition date: 2006-03-15, release date: 2006-05-09, Last modification date: 2024-03-13)
Primary citation	Johnson, D.J.,Li, W.,Adams, T.E.,Huntington, J.A. Antithrombin-S195A factor Xa-heparin structure reveals the allosteric mechanism of antithrombin activation. Embo J., 25:2029-2037, 2006 Cited by PubMed: 16619025 DOI: 10.1038/sj.emboj.7601089 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation