2GD4
Crystal Structure of the Antithrombin-S195A Factor Xa-Pentasaccharide Complex
Summary for 2GD4
Entry DOI | 10.2210/pdb2gd4/pdb |
Related PRD ID | PRD_900028 |
Descriptor | Coagulation factor X, Stuart factor, Stuart-Prower factor, Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain, Coagulation factor, Stuart factor, Stuart-Prower factor, Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain, Antithrombin-III, ... (9 entities in total) |
Functional Keywords | serpin, michaelis complex, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 173130.35 |
Authors | Johnson, D.J.,Li, W.,Adams, T.E.,Huntington, J.A. (deposition date: 2006-03-15, release date: 2006-05-09, Last modification date: 2024-03-13) |
Primary citation | Johnson, D.J.,Li, W.,Adams, T.E.,Huntington, J.A. Antithrombin-S195A factor Xa-heparin structure reveals the allosteric mechanism of antithrombin activation. Embo J., 25:2029-2037, 2006 Cited by PubMed: 16619025DOI: 10.1038/sj.emboj.7601089 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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