2G8R

The crystal structure of the RNase A- 3-N-piperidine-4-carboxyl-3-deoxy-ara-uridine complex

Summary for 2G8R

• Entry DOI: 10.2210/pdb2g8r/pdb
• Related: 2G8Q
• Descriptor: Ribonuclease pancreatic, 1-[3-(4-CARBOXYPIPERIDIN-1-YL)-3-DEOXY-BETA-D-ARABINOFURANOSYL]PYRIMIDINE-2,4(1H,3H)-DIONE (3 entities in total)
• Functional Keywords: hydrolase, ribonuclease, endonuclease
• Biological source: Bos taurus (cattle)
• Cellular location: Secreted: P61823
• Total number of polymer chains: 2
• Total formula weight: 28127.34

Authors

Leonidas, D.D.,Zographos, S.E.,Oikonomakos, N.G. (deposition date: 2006-03-03, release date: 2006-08-15, Last modification date: 2023-08-30)

• Primary citation: Leonidas, D.D.,Maiti, T.K.,Samanta, A.,Dasgupta, S.,Pathak, T.,Zographos, S.E.,Oikonomakos, N.G.; The binding of 3'-N-piperidine-4-carboxyl-3'-deoxy-ara-uridine to ribonuclease A in the crystal.; Bioorg.Med.Chem., 14:6055-6064, 2006; PubMed: 16730994; DOI: 10.1016/j.bmc.2006.05.011

Experimental method

X-RAY DIFFRACTION (1.7 Å)