2FW3
Crystal structure of rat carnitine palmitoyltransferase 2 in complex with antidiabetic drug ST1326
Summary for 2FW3
Entry DOI | 10.2210/pdb2fw3/pdb |
Descriptor | Carnitine O-palmitoyltransferase II, mitochondrial, (3R)-3-{[(TETRADECYLAMINO)CARBONYL]AMINO}-4-(TRIMETHYLAMMONIO)BUTANOATE (3 entities in total) |
Functional Keywords | central six-stranded beta-sheet, transferase |
Biological source | Rattus norvegicus (Norway rat) |
Cellular location | Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side : P18886 |
Total number of polymer chains | 1 |
Total formula weight | 73965.71 |
Authors | Rufer, A.C.,Thoma, R.,Benz, J.,Stihle, M.,Gsell, B.,De Roo, E.,Banner, D.W.,Mueller, F.,Chomienne, O.,Hennig, M. (deposition date: 2006-02-01, release date: 2007-02-01, Last modification date: 2024-03-13) |
Primary citation | Rufer, A.C.,Thoma, R.,Benz, J.,Stihle, M.,Gsell, B.,De Roo, E.,Banner, D.W.,Mueller, F.,Chomienne, O.,Hennig, M. The crystal structure of carnitine palmitoyltransferase 2 and implications for diabetes treatment Structure, 14:713-723, 2006 Cited by PubMed: 16615901DOI: 10.1016/j.str.2006.01.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report