2FSE
Crystallographic structure of a rheumatoid arthritis MHC susceptibility allele, HLA-DR1 (DRB1*0101), complexed with the immunodominant determinant of human type II collagen
Summary for 2FSE
Entry DOI | 10.2210/pdb2fse/pdb |
Descriptor | H-2 class II histocompatibility antigen, E-K alpha chain, HLA class II histocompatibility antigen, DRB1-1 beta chain, Collagen alpha-1(II), ... (4 entities in total) |
Functional Keywords | rheumatoid arthritis, hla-dr1, collagen type ii, antigen presentation, immune system, structural protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Single-pass type I membrane protein: P01903 P04229 Secreted, extracellular space, extracellular matrix : P02458 |
Total number of polymer chains | 6 |
Total formula weight | 87962.28 |
Authors | Ivey, R.A.,Rosloniec, E.F.,Whittington, K.B.,Kang, A.H.,Park, H.W. (deposition date: 2006-01-22, release date: 2006-09-19, Last modification date: 2017-10-18) |
Primary citation | Rosloniec, E.F.,Ivey, R.A.,Whittington, K.B.,Kang, A.H.,Park, H.W. Crystallographic Structure of a Rheumatoid Arthritis MHC Susceptibility Allele, HLA-DR1 (DRB1*0101), Complexed with the Immunodominant Determinant of Human Type II Collagen. J.Immunol., 177:3884-3892, 2006 Cited by PubMed: 16951351PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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