2FSE
Crystallographic structure of a rheumatoid arthritis MHC susceptibility allele, HLA-DR1 (DRB1*0101), complexed with the immunodominant determinant of human type II collagen
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | H-2 class II histocompatibility antigen, E-K alpha chain | polymer | 178 | 20711.2 | 2 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) In PDB | Homo sapiens (human) | |
2 | B, D | HLA class II histocompatibility antigen, DRB1-1 beta chain | polymer | 187 | 21909.4 | 2 | UniProt (P04229) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01911) In PDB | Mus musculus (house mouse) | |
3 | E, F | Collagen alpha-1(II) | polymer | 14 | 1360.5 | 2 | UniProt (P02458) In PDB | Homo sapiens (human) | |
4 | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 87962.3 | |
All* | Total formula weight | 87962.3 |