2FOV

Human Carbonic Anhydrase II complexed with two-prong inhibitors

Summary for 2FOV

Entry DOI	10.2210/pdb2fov/pdb
Related	2CBA 2FOQ 2FOS 2FOU 2FOY
Descriptor	Carbonic Anhydrase II, ZINC ION, COPPER (II) ION, ... (6 entities in total)
Functional Keywords	lyase, zinc, inhibitor, copper
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P00918
Total number of polymer chains	1
Total formula weight	30515.45
Authors	Jude, K.M.,Christianson, D.W. (deposition date: 2006-01-14, release date: 2006-04-04, Last modification date: 2023-08-30)
Primary citation	Jude, K.M.,Banerjee, A.L.,Haldar, M.K.,Manokaran, S.,Roy, B.,Mallik, S.,Srivastava, D.K.,Christianson, D.W. Ultrahigh resolution crystal structures of human carbonic anhydrases I and II complexed with two-prong inhibitors reveal the molecular basis of high affinity. J.Am.Chem.Soc., 128:3011-3018, 2006 Cited by PubMed: 16506782 DOI: 10.1021/ja057257n PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.15 Å)

Structure validation