2FOV
Human Carbonic Anhydrase II complexed with two-prong inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Carbonic Anhydrase II | polymer | 260 | 29503.7 | 1 | UniProt (P00918) Pfam (PF00194) In PDB | Homo sapiens (human) | Carbonic anhydrase II, Carbonate dehydratase II, CA-II, Carbonic anhydrase C |
| 2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | A | COPPER (II) ION | non-polymer | 63.5 | 1 | Chemie (CU) | |||
| 4 | A | {2,2'-[(2-{[4-(AMINOSULFONYL)BENZOYL]AMINO}ETHYL)IMINO]DIACETATO(2-)-KAPPAO}COPPER | non-polymer | 420.9 | 2 | Chemie (B30) | |||
| 5 | A | ACETONITRILE | non-polymer | 41.1 | 1 | Chemie (CCN) | |||
| 6 | water | water | 18.0 | 269 | Chemie (HOH) |
Sequence modifications
A: 2 - 260 (UniProt: P00918)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Cmh 206 | Cys 204 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29503.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1011.8 | |
| All* | Total formula weight | 30515.5 |
