2FJ0

Crystal Structure of Juvenile Hormone Esterase from Manduca sexta, with OTFP covalently attached

Summary for 2FJ0

Entry DOI	10.2210/pdb2fj0/pdb
Descriptor	Carboxylic ester hydrolase, 1,1,1-TRIFLUORO-3-(OCTYLTHIO)ACETONE (3 entities in total)
Functional Keywords	esterase, juvenile hormone, manduca sexta, alpha-beta hydrolase, hydrolase
Biological source	Manduca sexta (Carolina sphinx,hornblower,tobacco hawkmoth,tomato hornworm)
Total number of polymer chains	1
Total formula weight	62411.57
Authors	Wogulis, M.,Wilson, D.K. (deposition date: 2005-12-30, release date: 2006-05-23, Last modification date: 2015-06-10)
Primary citation	Wogulis, M.,Wheelock, C.E.,Kamita, S.G.,Hinton, A.C.,Whetstone, P.A.,Hammock, B.D.,Wilson, D.K. Structural studies of a potent insect maturation inhibitor bound to the juvenile hormone esterase of Manduca sexta. Biochemistry, 45:4045-4057, 2006 Cited by PubMed: 16566578 DOI: 10.1021/bi0521644 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation