2FBB

Crystal Structure Analysis of Hexagonal Lysozyme

Summary for 2FBB

Entry DOI	10.2210/pdb2fbb/pdb
Descriptor	Lysozyme C, SODIUM ION, NITRATE ION, ... (4 entities in total)
Functional Keywords	hexagonal lysozyme, hydrolase
Biological source	Gallus gallus (chicken)
Cellular location	Secreted: P00698
Total number of polymer chains	1
Total formula weight	15438.19
Authors	Brinkmann, C.,Weiss, M.S.,Weckert, E. (deposition date: 2005-12-09, release date: 2006-03-28, Last modification date: 2024-10-16)
Primary citation	Brinkmann, C.,Weiss, M.S.,Weckert, E. The structure of the hexagonal crystal form of hen egg-white lysozyme. Acta Crystallogr.,Sect.D, 62:349-355, 2006 Cited by PubMed Abstract: The three-dimensional structure of hen egg-white lysozyme (HEWL) in a hexagonal crystal form has been determined and refined to 1.46 A resolution. This hexagonal crystal form crystallizes from a saturated sodium nitrate solution at pH 8.4. The crystals belong to space group P6(1)22, with unit-cell parameters a = b = 85.64, c = 67.93 A. A total of 165 water molecules, 16 nitrate ions and five sodium ions were located in the electron-density map. The hexagonal crystal form exhibits a higher solvent content and a higher degree of disorder than other crystal forms of lysozyme. The flexibility of the protein depends on the crystal packing, although some residue ranges are flexible in all native HEWL crystal forms. PubMed: 16552135 DOI: 10.1107/S0907444906000825 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.46 Å)

Structure validation