2F91

1.2A resolution structure of a crayfish trypsin complexed with a peptide inhibitor, SGTI

Replaces:  1YR4

Summary for 2F91

• Entry DOI: 10.2210/pdb2f91/pdb
• Descriptor: hepatopancreas trypsin, Serine protease inhibitor I/II, CADMIUM ION, ... (5 entities in total)
• Functional Keywords: serine protease, trypsin, canonical inhibitor, atomic resolution, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Pontastacus leptodactylus (narrow-clawed crayfish); More
• Cellular location: Secreted: O46162
• Total number of polymer chains: 2
• Total formula weight: 29646.12

Authors

Fodor, K.,Harmat, V.,Hetenyi, C.,Kardos, J.,Antal, J.,Perczel, A.,Patthy, A.,Katona, G.,Graf, L. (deposition date: 2005-12-05, release date: 2006-04-18, Last modification date: 2023-08-30)

• Primary citation: Fodor, K.,Harmat, V.,Neutze, R.,Szilagyi, L.,Graf, L.,Katona, G.; Enzyme:Substrate Hydrogen Bond Shortening during the Acylation Phase of Serine Protease Catalysis.; Biochemistry, 45:2114-2121, 2006; PubMed: 16475800; DOI: 10.1021/bi0517133

Experimental method

X-RAY DIFFRACTION (1.2 Å)