2ERH
Crystal Structure of the E7_G/Im7_G complex; a designed interface between the colicin E7 DNAse and the Im7 immunity protein
Summary for 2ERH
Entry DOI | 10.2210/pdb2erh/pdb |
Related | 7CEI |
Descriptor | Colicin E7 immunity protein, Colicin E7 (3 entities in total) |
Functional Keywords | computational design, redesigned protein-protein interface, hydrogen bond network, specificity, molecular recognition, protein complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Escherichia coli More |
Total number of polymer chains | 2 |
Total formula weight | 24626.58 |
Authors | Joachimiak, L.A.,Kortemme, T.,Stoddard, B.L.,Baker, D. (deposition date: 2005-10-24, release date: 2006-07-25, Last modification date: 2023-08-23) |
Primary citation | Joachimiak, L.A.,Kortemme, T.,Stoddard, B.L.,Baker, D. Computational Design of a New Hydrogen Bond Network and at Least a 300-fold Specificity Switch at a Protein-Protein Interface. J.Mol.Biol., 361:195-208, 2006 Cited by PubMed: 16831445DOI: 10.1016/j.jmb.2006.05.022 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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