2E8V

S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with product GGPP (P21)

Summary for 2E8V

Entry DOI	10.2210/pdb2e8v/pdb
Related	2DH4 2E8T 2E8U 2E8W 2E8X 2E90 2E91 2E92 2E93 2E94 2E95 2E96 2E97
Descriptor	Geranylgeranyl pyrophosphate synthetase, GERANYLGERANYL DIPHOSPHATE (3 entities in total)
Functional Keywords	prenyltransferase, farnesyl pyrophosphate, bisphosphonate, transferase
Biological source	Saccharomyces cerevisiae (baker's yeast)
Cellular location	Cytoplasm (By similarity): Q12051
Total number of polymer chains	2
Total formula weight	79499.00
Authors	Chen, C.K.-M.,Guo, R.T.,Ko, T.P.,Jeng, W.Y.,Chang, T.H.,Liang, P.H.,Oldfield, E.,Wang, A.H.-J. (deposition date: 2007-01-23, release date: 2007-06-12, Last modification date: 2023-10-25)
Primary citation	Guo, R.T.,Cao, R.,Liang, P.H.,Ko, T.P.,Chang, T.H.,Hudock, M.P.,Jeng, W.Y.,Chen, C.K.-M.,Zhang, Y.,Song, Y.,Kuo, C.J.,Yin, F.,Oldfield, E.,Wang, A.H.-J. Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104:10022-10027, 2007 Cited by PubMed: 17535895 DOI: 10.1073/pnas.0702254104 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation