2E8V
S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with product GGPP (P21)
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004161 | molecular_function | dimethylallyltranstransferase activity |
A | 0004311 | molecular_function | farnesyltranstransferase activity |
A | 0004337 | molecular_function | geranyltranstransferase activity |
A | 0004659 | molecular_function | prenyltransferase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0005739 | cellular_component | mitochondrion |
A | 0008299 | biological_process | isoprenoid biosynthetic process |
A | 0015031 | biological_process | protein transport |
A | 0016114 | biological_process | terpenoid biosynthetic process |
A | 0016740 | molecular_function | transferase activity |
A | 0033384 | biological_process | geranyl diphosphate biosynthetic process |
A | 0033386 | biological_process | geranylgeranyl diphosphate biosynthetic process |
A | 0045337 | biological_process | farnesyl diphosphate biosynthetic process |
A | 0046872 | molecular_function | metal ion binding |
B | 0004161 | molecular_function | dimethylallyltranstransferase activity |
B | 0004311 | molecular_function | farnesyltranstransferase activity |
B | 0004337 | molecular_function | geranyltranstransferase activity |
B | 0004659 | molecular_function | prenyltransferase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0005739 | cellular_component | mitochondrion |
B | 0008299 | biological_process | isoprenoid biosynthetic process |
B | 0015031 | biological_process | protein transport |
B | 0016114 | biological_process | terpenoid biosynthetic process |
B | 0016740 | molecular_function | transferase activity |
B | 0033384 | biological_process | geranyl diphosphate biosynthetic process |
B | 0033386 | biological_process | geranylgeranyl diphosphate biosynthetic process |
B | 0045337 | biological_process | farnesyl diphosphate biosynthetic process |
B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 21 |
Details | BINDING SITE FOR RESIDUE GRG A 1501 |
Chain | Residue |
A | GLY40 |
A | LEU143 |
A | HIS144 |
A | GLN147 |
A | LYS174 |
A | TYR210 |
A | GLN211 |
A | HOH452 |
A | HOH492 |
A | HOH681 |
A | HOH1202 |
A | LYS41 |
A | HOH1351 |
A | HOH1352 |
A | ARG44 |
A | LEU72 |
A | HIS73 |
A | SER76 |
A | ARG90 |
A | TYR112 |
A | LEU140 |
site_id | AC2 |
Number of Residues | 18 |
Details | BINDING SITE FOR RESIDUE GRG B 1502 |
Chain | Residue |
B | GLY40 |
B | LYS41 |
B | ARG44 |
B | HIS73 |
B | SER76 |
B | ARG90 |
B | TYR112 |
B | HIS144 |
B | GLN147 |
B | LYS174 |
B | TYR210 |
B | GLN211 |
B | HOH403 |
B | HOH449 |
B | HOH524 |
B | HOH534 |
B | HOH667 |
B | HOH1130 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 20 |
Details | BINDING: BINDING => ECO:0000269|PubMed:17535895 |
Chain | Residue | Details |
A | LYS41 | |
A | LYS238 | |
B | LYS41 | |
B | ARG44 | |
B | HIS73 | |
B | ARG89 | |
B | ARG90 | |
B | LYS174 | |
B | THR175 | |
B | GLN211 | |
B | ASN218 | |
A | ARG44 | |
B | LYS238 | |
A | HIS73 | |
A | ARG89 | |
A | ARG90 | |
A | LYS174 | |
A | THR175 | |
A | GLN211 | |
A | ASN218 |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000269|PubMed:16554305, ECO:0000269|PubMed:17535895 |
Chain | Residue | Details |
A | ASP80 | |
A | ASP84 | |
B | ASP80 | |
B | ASP84 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000305|PubMed:17535895 |
Chain | Residue | Details |
A | LYS228 | |
B | LYS228 |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | SITE: Important for determining product chain length |
Chain | Residue | Details |
A | TYR112 | |
B | TYR112 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1fps |
Chain | Residue | Details |
A | TYR210 | |
A | ARG89 |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1fps |
Chain | Residue | Details |
B | TYR210 | |
B | ARG89 |