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2DW4

Crystal structure of human LSD1 at 2.3 A resolution

Summary for 2DW4
Entry DOI10.2210/pdb2dw4/pdb
DescriptorLysine-specific histone demethylase 1, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total)
Functional Keywordsdemethylase, amine oxidase, chromatin, histone, androgen, fad, corepressor, oxidoreductase, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi
Biological sourceHomo sapiens (human)
Cellular locationNucleus: O60341
Total number of polymer chains1
Total formula weight74235.52
Authors
Sengoku, T.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2006-08-02, release date: 2007-09-04, Last modification date: 2024-03-13)
Primary citationMimasu, S.,Sengoku, T.,Fukuzawa, S.,Umehara, T.,Yokoyama, S.
Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25A
Biochem.Biophys.Res.Commun., 366:15-22, 2008
Cited by
PubMed: 18039463
DOI: 10.1016/j.bbrc.2007.11.066
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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